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Tag Archives: long post

Yoga as a practice tool

31 Wednesday May 2023

Posted by RichardB in Coping Skills, Wellness

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long post, research, yoga

Today more and more adults practice yoga, and not surprisingly, there is research supporting its physical benefits. Studies show the practice—which combines stretching and other exercises with deep breathing and meditation—can improve overall physical fitness, strength, flexibility and lung capacity, while reducing heart rate, blood pressure and back pain.

But what is perhaps unknown to those who consider yoga just another exercise form is that there is a growing body of research documenting yoga’s psychological benefits. Several recent studies suggest that yoga may help strengthen social attachments, reduce stress and relieve anxiety, depression and insomnia. Researchers are also starting to claim some success in using yoga and yoga-based treatments to help active-duty military and veterans with post-traumatic stress disorder.

“The evidence is showing that yoga really helps change people at every level,” says Stanford University health psychologist and yoga instructor Kelly McGonigal, PhD.

That’s why more clinicians have embraced yoga as a complement to psychotherapy, McGonigal says. They’re encouraging yoga as a tool clients can use outside the therapy office to cope with stress and anxieties, and even heal emotional wounds.

“Talk therapy can be helpful in finding problem-solving strategies and understanding your own strengths and what’s happening to you, but there are times when you just need to kind of get moving and work through the body,” says Melanie Greenberg, PhD, a psychology professor at Alliant International University, who has studied yoga’s benefits to mental health.

The mind-body meld

According to a study by Sherry A. Glied, PhD, professor of health policy and management at Columbia University, and Richard G. Frank, PhD, professor of health-care policy at Harvard Medical School, published in the May/June Health Affairs (Vol. 28, No. 3), the rate of diagnosed cases of mental disorders increased dramatically between 1996 and 2006—doubling among adults age 65 and older, and rising by about 60 percent among adults 18 to 64. During that same time period, rates of psychotropic medication use rose by about the same percentages among these groups.

In light of these numbers, yoga remains a natural and readily available approach to maintaining wellness and treating mental health issues, says Sat Bir Khalsa, PhD, a neuroscientist and professor of medicine at Harvard Medical School at Brigham and Women’s Hospital in Boston who studies yoga’s effects on depression and insomnia. Khalsa, who has practiced yoga for more than 35 years, says several studies in his 2004 comprehensive review of yoga’s use as a therapeutic intervention, published in the Indian Journal of Physiology and Pharmacology (Vol. 48, No. 3), show that yoga targets unmanaged stress, a main component of chronic disorders such as anxiety, depression, obesity, diabetes and insomnia. It does this, he says, by reducing the stress response, which includes the activity of the sympathetic nervous system and the levels of the stress hormone cortisol. The practice enhances resilience and improves mind-body awareness, which can help people adjust their behaviors based on the feelings they’re experiencing in their bodies, according to Khalsa.

While scientists don’t have quite the full picture on how yoga does all that, new research is beginning to shed light on how the practice may influence the brain. In a 2007 study in the Journal of Alternative and Complementary Medicine (Vol. 13, No. 4), researchers at Boston University School of Medicine and McLean Hospital used magnetic resonance imaging to compare levels of the neurotransmitter gamma-aminobutyric acid (GABA) before and after two types of activities: an hour of yoga and an hour of reading a book. The yoga group showed a 27 percent increase in GABA levels, which evidence suggests may counteract anxiety and other psychiatric disorders. GABA levels of the reading group remained unchanged.

“I believe if everyone practiced the techniques of yoga, we would have a preventive aid to a lot of our problems,” Khalsa says. “There would likely be less obesity and Type-II diabetes, and people would be less aggressive, more content and more integrated.”

Khalsa’s claims are backed by evidence supporting the social benefits of participating in a yoga class, says Stanford’s McGonigal. A series of experiments conducted by organizational behavior researchers at Stanford University and published in January’s Psychological Science (Vol. 20, No. 1) suggest that acting in synchrony with others—be it while walking, singing or dancing—can increase cooperation and collectivism among group members.

“In a yoga class, everyone is moving and breathing in at the same time and I think that’s one of the undervalued mechanisms that yoga can really help with: giving people that sense of belonging, of being part of something bigger,” McGonigal says.

Psychologists are also examining the use of yoga with survivors of trauma and finding it may even be more effective than some psychotherapy techniques. In a pilot study at the Trauma Center at the Justice Resource Institute in Brookline, Mass., women with PTSD who took part in eight sessions of a 75-minute Hatha yoga class experienced significantly reduced PTSD symptoms compared with those participating in a dialectical behavior therapy group. The center recently received a grant from the National Center for Complementary and Alternative Medicine to conduct a randomized, single-blind, controlled study to further examine whether, as compared with a 10-week health class, yoga improves the frequency and severity of PTSD symptoms and other somatic complaints as well as social and occupational impairments among female trauma survivors.

“When people experience trauma, they may experience not only a sense of emotional disregulation, but also a feeling of being physically immobilized,” says Ritu Sharma, PhD, project coordinator of the center’s yoga program, who only began practicing yoga when she started leading the program. “Body-oriented techniques such as yoga help them increase awareness of sensations in the body, stay more focused on the present moment and hopefully empower them to take effective actions.”

And in what is becoming one of the most widely applied yoga-based trauma treatments, clinical psychologist Richard Miller, PhD, has developed a nine-week, twice-weekly integrative restoration program based on the ancient practice of yoga Nidra. In 2006, the Department of Defense began testing iRest with active-duty soldiers returning from Iraq and Afghanistan who were experiencing PTSD. At the end of the program, participants reported a reduction in insomnia, depression, anxiety and fear, improved interpersonal relations and an increased sense of control over their lives. Since then, iRest classes have been established at VA facilities in Miami, Chicago and Washington, D.C. Miller has also helped develop similar programs for veterans, homeless people and those with chemical dependencies and chronic pain.

“The program teaches them skills they can integrate into their daily lives, so that in the midst of a difficult circumstance, they have the tools to be able to work in the moment,” says Miller, president of the Integrative Restoration Institute in San Rafael, Calif.

New research is also supporting yoga’s benefit for other mental illnesses. An as-yet-unpublished randomized control trial by Khalsa offers insight into how yoga may reduce insomnia. In this study, 20 participants who practiced a daily 45-minute series of Kundalini yoga techniques shortly before bedtime for eight weeks reported significant reductions in insomnia severity as compared with those told to follow six behavioral recommendations for sleep hygiene. And a 2007 study supports yoga’s potential as a complementary treatment for depressed patients taking antidepressant medication but only in partial remission. University of California, Los Angeles, psychologist David Shapiro, PhD, found that participants who practiced Iyengar yoga three times a week for eight weeks reported significant reductions in depression, anxiety and neurotic symptoms, as well as mood improvements at the end of each class (Evidence-based Complementary and Alternative Medicine, Vol. 4, No. 4). Many of the participants achieved remission and also showed physiological changes, such as heart rate variability, indicative of a greater capacity for emotional regulation, Shapiro says.

Putting yoga into practice

While she cautions against teaching yoga to clients without formal training, McGonigal and others say psychologists can use psychotherapy sessions to practice yoga’s mind-body awareness and breathing techniques. Simple strategies—such as encouraging clients to get as comfortable as possible during their sessions or to pay attention to how their body feels when they inhale and exhale—teach clients to be in the here and now.

“These by themselves would be considered yoga interventions because they direct attention to the breath and help unhook people from thoughts, emotions and impulses that are negative or destructive,” she says.

Alliant International University psychology professor Richard Gevirtz, PhD, agrees that alternatives to traditional psychotherapy may help clinicians make progress with difficult clients.

“Psychologists have painted themselves in the corner by only doing talk therapy,” Gevirtz says. “There’s much more that can be accomplished if you integrate it with other sorts of modalities, such as biofeedback, relaxation training or yoga.”

In fact, some psychologists say yoga may not really be so special when it comes to improving one’s mental state, and that several forms of exercise may provide mood-enhancing benefits.

In a 2007 study by researchers at Bowling Green State University, 36 participants kept mood diaries during the first and final four weeks of a 16-week weight-loss program. On the days participants engaged in planned exercise—typically walking for 30 to 60 minutes—they reported a better mood at night as compared to in the morning, before exercising (Journal of Sport & Exercise Psychology, Vol. 29, No. 6).

“It seems that many types of exercise—particularly non-competitive exercise—are related to positive mood alteration,” says Bonnie Berger, EdD, one of the study’s co-authors and professor and director of Bowling Green’s School of Human Movement, Sport and Leisure Studies.

Psychologists may also benefit from using yoga and other forms of exercise for their own care, Greenberg says. In a 2007 survey of licensed APA members by the APA Board of Professional Affairs Advisory Committee on Colleague Assistance, 48 percent reported that vicarious trauma and compassion fatigue are likely to affect their functioning.

“Practicing yoga personally and adopting a stance based on yoga principles such as non-judgment, compassion, spirituality and the connection of all living things can help relieve stress, enhance compassion and potentially make you a better therapist,” she says. “If you can come to a level of peace with yourself, there may be more nurturing that you exude toward your patients.”

Drugs and the Brain

17 Wednesday May 2023

Posted by RichardB in Addiction, brain

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brain, drugs, long post

The human brain is the most complex organ in the body. This three-pound mass of gray and white matter sits at the center of all human activity—you need it to drive a car, to enjoy a meal, to breathe, to create an artistic masterpiece, and to enjoy everyday activities. In brief, the brain regulates your body’s basic functions; enables you to interpret and respond to everything you experience; and shapes your thoughts, emotions, and behavior.

The brain is made up of many parts that all work together as a team. Different parts of the brain are responsible for coordinating and performing specific functions. Drugs can alter important brain areas that are necessary for life-sustaining functions and can drive the compulsive drug abuse that marks addiction. Brain areas affected by drug abuse include:

  • The brain stem, which controls basic functions critical to life, such as heart rate, breathing, and sleeping.
  • The cerebral cortex, which is divided into areas that control specific functions. Different areas process information from our senses, enabling us to see, feel, hear, and taste. The front part of the cortex, the frontal cortex or forebrain, is the thinking center of the brain; it powers our ability to think, plan, solve problems, and make decisions.
  • The limbic system, which contains the brain’s reward circuit. It links together a number of brain structures that control and regulate our ability to feel pleasure. Feeling pleasure motivates us to repeat behaviors that are critical to our existence. The limbic system is activated by healthy, life-sustaining activities such as eating and socializing—but it is also activated by drugs of abuse. In addition, the limbic system is responsible for our perception of other emotions, both positive and negative, which explains the mood-altering properties of many drugs.

How do the parts of the brain communicate?

The brain is a communications center consisting of billions of neurons, or nerve cells. Networks of neurons pass messages back and forth among different structures within the brain, the spinal cord, and nerves in the rest of the body (the peripheral nervous system). These nerve networks coordinate and regulate everything we feel, think, and do.

  • Neuron to Neuron
    Each nerve cell in the brain sends and receives messages in the form of electrical and chemical signals. Once a cell receives and processes a message, it sends it on to other neurons.
  • Neurotransmitters – The Brain’s Chemical Messengers
    The messages are typically carried between neurons by chemicals called neurotransmitters.
  • Receptors – The Brain’s Chemical Receivers
    The neurotransmitter attaches to a specialized site on the receiving neuron called a receptor. A neurotransmitter and its receptor operate like a “key and lock,” an exquisitely specific mechanism that ensures that each receptor will forward the appropriate message only after interacting with the right kind of neurotransmitter.
  • Transporters – The Brain’s Chemical Recyclers
    Located on the neuron that releases the neurotransmitter, transporters recycle these neurotransmitters (that is, bring them back into the neuron that released them), thereby shutting off the signal between neurons.

To send a message, a brain cell (neuron) releases a chemical (neurotransmitter) into the space (synapse) between it and the next cell. The neurotransmitter crosses the synapse and attaches to proteins (receptors) on the receiving brain cell. This causes changes in the receiving cell—the message is delivered.

How do drugs work in the brain?

Drugs are chemicals that affect the brain by tapping into its communication system and interfering with the way neurons normally send, receive, and process information. Some drugs, such as marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter. This similarity in structure “fools” receptors and allows the drugs to attach onto and activate the neurons. Although these drugs mimic the brain’s own chemicals, they don’t activate neurons in the same way as a natural neurotransmitter, and they lead to abnormal messages being transmitted through the network.

Other drugs, such as amphetamine or cocaine, can cause the neurons to release abnormally large amounts of natural neurotransmitters or prevent the normal recycling of these brain chemicals. This disruption produces a greatly amplified message, ultimately disrupting communication channels.

How do drugs work in the brain to produce pleasure?

Most drugs of abuse directly or indirectly target the brain’s reward system by flooding the circuit with dopamine. Dopamine is a neurotransmitter present in regions of the brain that regulate movement, emotion, motivation, and feelings of pleasure. When activated at normal levels, this system rewards our natural behaviors. Overstimulating the system with drugs, however, produces euphoric effects, which strongly reinforce the behavior of drug use—teaching the user to repeat it.

Most drugs of abuse target the brain’s reward system by flooding it with dopamine.

How does stimulation of the brain’s pleasure circuit teach us to keep taking drugs?

Our brains are wired to ensure that we will repeat life-sustaining activities by associating those activities with pleasure or reward. Whenever this reward circuit is activated, the brain notes that something important is happening that needs to be remembered, and teaches us to do it again and again without thinking about it. Because drugs of abuse stimulate the same circuit, we learn to abuse drugs in the same way.

Why are drugs more addictive than natural rewards?

When some drugs of abuse are taken, they can release 2 to 10 times the amount of dopamine that natural rewards such as eating and sex do. In some cases, this occurs almost immediately (as when drugs are smoked or injected), and the effects can last much longer than those produced by natural rewards. The resulting effects on the brain’s pleasure circuit dwarf those produced by naturally rewarding behaviors. The effect of such a powerful reward strongly motivates people to take drugs again and again. This is why scientists sometimes say that drug abuse is something we learn to do very, very well.

Long-term drug abuse impairs brain functioning.

What happens to your brain if you keep taking drugs?

For the brain, the difference between normal rewards and drug rewards can be described as the difference between someone whispering into your ear and someone shouting into a microphone. Just as we turn down the volume on a radio that is too loud, the brain adjusts to the overwhelming surges in dopamine (and other neurotransmitters) by producing less dopamine or by reducing the number of receptors that can receive signals. As a result, dopamine’s impact on the reward circuit of the brain of someone who abuses drugs can become abnormally low, and that person’s ability to experience any pleasure is reduced.

This is why a person who abuses drugs eventually feels flat, lifeless, and depressed, and is unable to enjoy things that were previously pleasurable. Now, the person needs to keep taking drugs again and again just to try and bring his or her dopamine function back up to normal—which only makes the problem worse, like a vicious cycle. Also, the person will often need to take larger amounts of the drug to produce the familiar dopamine high—an effect known as tolerance.

Decreased Dopamine Transporters in a Methamphetamine Abuser

How does long-term drug taking affect brain circuits?

We know that the same sort of mechanisms involved in the development of tolerance can eventually lead to profound changes in neurons and brain circuits, with the potential to severely compromise the long-term health of the brain. For example, glutamate is another neurotransmitter that influences the reward circuit and the ability to learn. When the optimal concentration of glutamate is altered by drug abuse, the brain attempts to compensate for this change, which can cause impairment in cognitive function. Similarly, long-term drug abuse can trigger adaptations in habit or non-conscious memory systems. Conditioning is one example of this type of learning, in which cues in a person’s daily routine or environment become associated with the drug experience and can trigger uncontrollable cravings whenever the person is exposed to these cues, even if the drug itself is not available. This learned “reflex” is extremely durable and can affect a person who once used drugs even after many years of abstinence.

What other brain changes occur with abuse?

Chronic exposure to drugs of abuse disrupts the way critical brain structures interact to control and inhibit behaviors related to drug use. Just as continued abuse may lead to tolerance or the need for higher drug dosages to produce an effect, it may also lead to addiction, which can drive a user to seek out and take drugs compulsively. Drug addiction erodes a person’s self-control and ability to make sound decisions, while producing intense impulses to take drugs.

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