Self-Control Can Be Draining

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The human body has a finite number of resources, and scientists are always discovering more about how these resources are shared, depleted, and replenished. Now a new study suggests that the areas in your brain responsible for self-control and forming memories are closely linked – in other words, if you’re concentrating hard on staying disciplined, you’re probably becoming less adept at remembering what’s happening.

Researchers Yu-Chin Chiu and Tobias Egner from Duke University in the US asked a group of volunteers to recognize a series of faces, both with and without the inclusion of a self-control test in the middle. They found that having to exercise self-control had a negative impact on the participants’ ability to recall which pictures they’d previously seen. The same experiment was then repeated with a new set of volunteers and brain-scanning fMRI (functional magnetic resonance imaging) equipment on hand.

The pair discovered that one area of the brain – the ventrolateral prefrontal cortex – was activated frequently during the self-control test and predicted the strength of the volunteers’ memory later on. The findings suggest that self-control and memory compete for the same resources inside the brain and support the theory that inhibiting ourselves can also cause us to forget more easily.

“The control demands of response inhibition divert attention away from stimulus encoding, thereby weakening memory traces for inhibitory cues,” the researchers conclude in The Journal of Neurosience. “These findings shed new light on the relation between the control process of response inhibition and the cognitive domains of perception, attention, and memory.”

The self-control test used was a traditional Go/No-Go task: these tasks work by asking participants to view a series of items and push a button only when certain criteria are met – in the case of this experiment, when the face shown is male rather than female. The theory is that those who are able to hold back from a button push when necessary are those with the strongest self-control (or “response inhibition”, as neuroscientists like to call it). The participants were not told in advance that they would need to remember the faces they were shown.

“The scans revealed that responding to a cue and inhibiting a response produced overlapping activation patterns in brain regions within the right frontal and parietal lobes, a network that has previously been implicated in response inhibition,” Mo Costrandi reports for The Guardian. “Crucially, ‘no-go’ trials produced greater activation of this network than ‘Go’ trials, and activity in one specific brain region (the ventrolateral prefrontal cortex) predicted the strength of the participants’ memory, such that the greater the observed network activation, the more likely the participants were to forget that face later on.”

The researchers admit their theory is still “speculative” for now, but if further study confirms the link, they believe their discovery could be used to treat people who have problems with self-control: those suffering from ADHD (Attention Deficit Hyperactivity Disorder), for example, or some form of addiction.

One scenario put forward by the pair is having to suddenly cancel a lane change on the motorway because a car is already in the spot you want to move into. If they’re right, the act of having to control and inhibit your actions would make it less likely that you would remember the details of the incident – such as the make and model of the car that was blocking your path.

Irrational Beliefs Guide

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Consider the following questions carefully. Reflectively answer each one briefly but completely regarding those people or things about which you are most emotionally disturbed. This assignment may be emotionally painful, but it may help you achieve needed insight so that you can end your pain.

  • Who or what disturbs or upsets you?
  • Who or what do you strongly believe should, ought, must, or have to be different?
  • Who or what do you strongly think is or awful, terrible, horrible, or catastrophic?
  • Who or what do you down, damn, condemn or believe is worthless?
  • Who or what do you believe is absolutely needed, necessary, or required?
  • What are the things you strongly believe are absolutes, extremes, or critically important?
  • Who or what do you most often or most strongly complain about?
  • What is your greatest wish that you believe you most likely won’t get?
  • What goal have you made (even unconsciously) into a demand because you not only want to but have convinced yourself you must achieve it?
  • What happened in your past from which you cannot recover?
  • What things do you find are, too hard, too much, too painful, too upsetting, or that you just can’t stand?
  • Who or what are you most likely to lose your temper over?
  • What are the biggest stresses in your life?
  • Who or what do you feel most helpless about?
  • Who or what do you feel most hopeless about?
  • What are your most strongly felt demands, wishes, or hopes?
  • What insight or awareness have you come to because of this exercise?

Neuroscience, Addiction, Theory

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Over the years I have read articles and case files of clients that suggest there is an abundance of anxiety and anxiety related disorders with people who experience alcohol and drug addiction. One of the chief components that produce anxiety is stress and according to Volkow and Li (2005) stress increases vulnerability to drug use and relapse in those addicted. They both argue that there is evidence that, “corticotropin-releasing factor (CRF) might play a linking role through its effects on the mesocorticolimbic dopamine system and the hypothalamic-pituitary–adrenal axis15-16” (Volkow, Li, 2005, p 1429). In simpler terms, stress produces CRF which affects the limbic system and the adrenals which in turn increases the stress response cycle.

In thinking about stress I stumbled across another article in the same issue of Nature and Neuroscience that talked about stress like responses, abet in a somewhat indirect manner. The article, by Antoine Bechara (2005) talks about the amygdala being out of balance. Bechara argues that addicted people become unable to make drug-use choices on the basis of long-term outcome because of hyperactivity within the amygdala (Bechara, 2005, p.1458). The amygdala which signals pain or pleasure of immediate prospects, overpowers the reflective prefrontal cortex system for signaling pain or pleasure of future prospects thus altering the decision making process. Bachara goes on to say that substance use can trigger involuntary signals originating from the amygdala that modulate, bias or even hijack the goal-driven cognitive resources that are needed for the normal operation of the reflective system and for exercising the willpower to resist drugs (Bechara, 2005, p.1458).

Knowing the basics that there is a relationship between the amygdala, drug use and stress I am willing to hypothesize that there is a circular connection here. Stress (and drug use) changes the composition of the chemicals that move through the body, this changed composition changes us more by altering the functions in the amygdala, which leads to changes in the decision making process. This combination of factors (stress-chemical composition-amygdala- and temperament) could be an over whelming force.

In fact, as long as I am going out on a limb and possibly completely limbless, I hypothesize that this stress amygdala cycle maybe related to the high/low reactive response Kagan noticed behaviorally in infants some thirty plus years ago at Harvard.

From Kagan’s perspective, temperament is an emotional/behavioral bias, independent of cognitive abilities, that affects receptivity to certain moods and emotions (Mitchell, 2006). Temperament has an effect on the neural chemistry of the brain and thus the sensitivity of certain receptors. Kagan theorized this is based on inherited factors that control the amygdala and thus the production of chemicals in the brain (Mitchell, 2006). This sensitivity, Kagan believes, is the basis of the behavioral/temperamental aspect of an individual.

In Kagan’s theory the chemical production of the amygdala alters receptor connections forming what he describes as high and low reactive (Mitchell, 2006). A high reactive is a high level of arousal to stimuli (crying), versus a low reactive which has a more relaxed reaction to stimuli. Highs have a more active amygdala, and tend to need to be in more control (control their responses and avoid the high reactive reactions).

Thus Bechara theory that drugs stimulate the amygdala maybe the same responses/reactions that Kagan saw in high reactive individuals. If one is a high reactive addict and you are surrounded by stimuli your inherent reaction is to want to control your high response because it creates tension within. The addict wants to quiet the tension, and the brain remembers that using fills that immediate need for control by quieting the reactions. But the drug use only temporally gives control as it also creates a hyperactive response in the amygdala which also reinforces that experience/feeling/thought that it’s more important to use now and not worry about later.

This hypothetical situation might manifest itself somatically by the addict contracting in response to memories of the original or current stressor stimuli for example. This contraction may have become neurologically and psychologically habituated as, “the body movements we develop when we are young are the modus operandi of dissociating” (Caldwell, 1996, p. 28). This contraction would possibly be followed by the person moving to remedy the situation by desensitization through a known movement pattern of perhaps contraction and release. This contraction/release could be a strain/release pattern, followed by a stop/go hesitation pattern as the person struggles with the need to control/quiet the self and the amygdala sends signals/memories of use that overrule the reflective prefrontal cortex. The person uses and goes into a running/drifting rhythm followed by even flow as the effects of the usage wears off.

Despite some 40 plus years of working with folks using movement and therapy I am still learning about movement and its relationship to addictions and disorders (disharmony) in general. I feel like I am also in the beginning stages of learning about neuroscience and the body with its behaviors. I get a wee bit excited when I think about the journals and articles that I have had only a chance to skim or read once and the connections with addictions as well as Kagan, Bachara, Volkow, Li, and others theories of addiction and personality. I never would have thought I would spend so much time looking at addictions but I see in adults with addictions many issues; adolescence, child hood trauma, dysfunctional families, depression, anxiety, low self esteem, disassociation from the body and from feelings. One population with many pathologies, just like every other population (humans) I suppose.

References

AHD, American Heritage Dictionary of the English Language, Fourth Edition. (2000) Houghton Mifflin Company. Retrieved February 28 2008 from Yahoo Education and Reference Dictionary at http://education.yahoo.com/reference/dictionary/entry/addiction

Ballas,C. MD. (2008). Medical Encyclopedia: Addiction. Retrieved February 27 2008 from National Institutes of Health at http://www.nlm.nih.gov/medlineplus/ency/article/001522.htm

Bechara, A. (2005). Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nature Neuroscience. Vol 8, no. 11 Novemenber 2005.

Cadlwell, C. (1996). Getting our bodies back. Boston: Shambahala.

Capello, P,P. (2008). Dance/Movement Therapy with Children Throughout the World. American Journal Dance Therapy. (2008) Vol. 30. pg: 24–36

Fisher, B. MA, DTR. (1990). Dance/Movement Therapy:Its use in a 28 day substance abuse program. The Arts in Psychotherapy. Vol 17, pp.325-331

Fraser, J. S., & Solovey, A. D. (2007). Substance Abuse and Dependency. Second-order change in psychotherapy: The golden thread that unifies effective treatments., 223-244.  

Lewis, P. (2003) Marian Chace Foundation Annual Lecture: Dancing with the Movement of the River. American Journal of Dance Therapy Vol. 25, No. 1, Spring/Summer 2003

Milliken, R. (1990). Dance/movement therapy with the substance abuser. The Arts in Psychotherapy, The creative arts therapies in the treatment of substance abuse, 17(4), 309-317.

Mitchell, N. (2006, August 26). All in the mind: Jerome Kagan, the father of temperament. Australia Broadcast Corporation, Radio National. Retrieved August 26, 2006, from http://abc.net.au/rn/aim/

TIPS, National Library of Medicine. (2008). Groups and substance abuse treatment: From Treatment Improvement Protocol Series. Retrieved February 25 2008 from Health Services Technology/Assessment Texts http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=hstat5.section.78466

NIDA, National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA). (2008). NIDA Info-Facts: Nationwide Trends. Retrieved February 22 2008 from U.S. Department of Health and Human Services. http://www.nida.nih.gov/Infofacts/nationtrends.html

Volkow,N. Li, Ting-Kai. (2005). The neuroscience of addiction. Nature Neuroscience. Vol 8, no. 11 Novemenber 2005 .

Rose,S. (1995). Movement as metaphor in treating chemical addiction. In F.J. Levy (Ed.), Dance and other expressive art therapies. New York: Routledge.

Evidence based Yoga 2

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Yoga is a mind and body practice in complementary medicine with origins in ancient Indian philosophy. Part two of evidence based Yoga:

Carpal tunnel syndrome A randomized, single-blind controlled trial of 42 patients with carpal tunnel syndrome assigned subjects to either a yoga treatment group or a wrist splint group, each 8 weeks in duration. Twice a week, the yoga group practiced postures specifically designed to strengthen and stretch each joint in the upper body. Yoga participants showed improvement in grip strength, pain levels, and Phalen’s sign when compared to the wrist splint group. Nerve conduction studies were not performed.15 A Cochrane review of 21 trials that evaluated the clinical outcome of nonsurgical treatment of carpal tunnel syndrome reported that 8 weeks of yoga practice significantly reduced pain as compared to wrist splinting. The yoga was described as having a “significant short-term benefit,” though the duration of this benefit is unknown.16

dog1

Depression A 2004 review of five RCTs that evaluated yoga-based interventions for depression and depressive disorders showed some positive outcomes and no adverse effects on patients’ mild to severe depressive disorders. However, poor study design and incomplete methodologic reporting makes this interpretation preliminary.17 An RCT studying 7 weeks of yoga training in a group of breast cancer survivors showed positive changes in emotional function, depression, and mood disturbance.18 “Yoga and stress management” (in the online version of this article) provides more information on this study and others involving the effects of yoga on stress.

Irritable bowel syndrome In an RCT, treatment with loperamide (Imodium) was compared to treatment with a series of 12 yoga postures practiced twice a day for 2 months in a small sample of patients with clinically diagnosed irritable bowel syndrome. Patients underwent measurement of surface electrogastrography, and trait and state anxiety tests were administered before, during, and up to 2 months after treatment. Both intervention groups demonstrated a decrease in bowel symptoms and state anxiety.19

Menopausal symptoms In a recent pilot study, 14 postmenopausal women reported via interview and questionnaire a decrease in the severity and frequency of hot flushes after 8 weeks of 90-minute “restorative yoga” classes. Although this initial finding sounds encouraging, this trial had no control group or objective parameter measurements.20 An RCT studying postmenopausal sleep quality divided 164 women into groups who participated in either 4 months of low-intensity yoga, a moderate-intensity walking program, or a wait-list control group. This study reported no statistically significant interventional effects of any treatment on total sleep quality or on any individual sleep quality domain.21

Multiple sclerosis An RCT of 57 subjects with clinically defined multiple sclerosis were assigned to weekly Iyengar yoga class plus home practice, a cycling program, or a wait-list control group for 6 months. Results showed that both active interventions produced significant improvement in perceived levels of energy and reduced fatigue; however, the specific effects of the yoga practice were not isolated.22 Osteoarthritis In a pilot study, 11 deconditioned, yoga naive subjects with a clinical diagnosis of knee osteoarthritis showed improvements in pain and knee stiffness after 8 weeks of yoga training. The group performed modified Iyengar yoga sessions once a week.23

Seizure disorders In 2000, a systematic review of the published literature revealed that only one study was able to meet the selection criteria for reliable research design. The reviewers concluded that no available evidence pointed to yoga therapy as an efficacious treatment for epilepsy.24

Strength and flexibility In a recent study on the fitness related effects of hatha yoga, 10 yoga-naïve and previously untrained subjects aged 18 to 27 years participated in 85 minutes of pranayama and hatha yoga practice twice a week for 8 weeks. These subjects showed significant improvement in upper and lower body muscular strength, endurance, and flexibility. No statistically significant change in body composition or pulmonary function was observed.13
In a partial RCT with a longer time frame, 54 subjects aged 20 to 25 years participated in either 5 months of yoga instruction or no activity. After that time period, both groups practiced yoga for an additional 5 months. The group practicing 10 months of yoga showed significant improvements in shoulder, trunk, hip, and neck flexibility, as well as a reported improved performance during submaximal exercise testing.25
A well-executed study compared subjects who underwent 24 hours of hatha yoga classes over 8 weeks with a control group. The yoga training group showed a 13% to 35% improvement in flexibility, balance, and muscular endurance. The authors concluded that hatha yoga practice has significant effects on balance and flexibility.26

REFERENCES

1. Tindle HA, Davis RB, Phillips RS, Eisenberg DM. Trends in use of complementary and alternative medicine by US adults: 1997-2002. Altern Ther Health Med. 2005;11(1):42-49.
2. Carrico M. Yoga Journal’s Yoga Basics: The Essential Beginner’s Guide to Yoga for a Lifetime of Health and Fitness. New York, NY: Henry Holt and Company; 1997.
3. Nayak NN, Shankar K. Yoga: a therapeutic approach. Phys Med Rehabil Clin N Am. 2004;15(4): 783-798, vi.
4. Innes KE, Bourguignon C, Taylor AG. Risk indices associated with the insulin resistance syndrome, cardiovascular disease, and possible protection with yoga: a systematic review.J Am Board Fam Pract. 2005;18(6):491-519.
5. Raub JA. Psychophysiologic effects of Hatha yoga on musculoskeletal and cardiopulmonary function: a literature review. J Altern Complement Med. 2002;8(6):797-812.
6. Luskin FM, Newell KA, Griffith M, et al. A review of mind-body therapies in the treatment of musculoskeletal disorders with implications for the elderly. Altern Ther Health Med. 2000;6(2): 46-56.
7. Jensen PS, Kenny DT. The effects of yoga on the attention and behavior of boys with attentiondeficit/ hyperactivity disorder (ADHD). J Atten Disord. 2004;7(4):205-216.
8. Kirkwood G, Rampes H, Tuffrey V, et al. Yoga for anxiety: a systematic review of the research evidence. Br J Sports Med. 2005;39(12):884-891.
9. Krisanaprakornkit T, Krisanaprakornkit W, Piyavhatkul N, Laopaiboon M. Meditation therapy for anxiety disorders. Cochrane Database Syst Rev. 2006;(1):CD004998.
10. Sabina AB, Williams AL, Wall HK, et al. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005;94(5):543-548.
11. Vendanthan PK, Kesavalu LN, Murthy KC, et al. Clinical study of yoga techniques in university students with asthma: a controlled study. Allergy Asthma Proc. 1998;19(1):3-9.
12. Sherman KJ, Cherkin DC, Erro J, et al. Comparing yoga, exercise, and a self-care book for chronic low back pain: a randomized, controlled trial. Ann Intern Med. 2005;143(12):849-856.
13. Tran MD, Holly RG, Lashbrook J, Amsterdam EA. Effects of Hatha yoga practice on the healthrelated aspects of physical fitness. Prev Cardiol. 2001;4(4):165-170.
14. Clay CC, Lloyd LK, Walker JL, et al. The metabolic cost of Hatha yoga. J Strength Cond Res. 2005;19(3):604-610.
15. Garfinkel MS, Singhal A, Katz WA, et al. Yoga-based intervention for carpal tunnel syndrome: a randomized trial. JAMA. 1998;280(18):1601-1603.
16. O’Connor D, Marshall S, Massy-Westropp N. Nonsurgical treatment (other than steroid injection) for carpal tunnel syndrome. Cochrane Database Syst Rev. 2003(1):CD003219.
17. Pilkington K, Kirkwood G, Rampes H, Richardson J. Yoga for depression: the research evidence. J Affect Disord. 2005;89(1-3):13-24.
18. Culos-Reed SN, Carlson LE, Daroux LM, Hately-Aldous S. A pilot study of yoga for breast cancer survivors: physical and psychological benefits. Psycho Oncol. 2006;15(10):891-897.
19. Taneja I, Deepak KK, Poojary G, et al. Yogic versus conventional treatment in diarrheapredominant irritable bowel syndrome: a randomized control study. Appl Psychophysiol Biofeedback. 2004;29(1):19-33.
20. Cohen BE, Kanaya AM, Macer JL, et al. Feasibility and acceptability of restorative yoga for treatment of hot flushes: a pilot trial. Maturitas. 2007;56(2):198-204.
21. Elavsky S, McAuley E. Lack of perceived sleep improvement after 4-month structured exercise programs. Menopause. 2007;14(3, pt 1):535-540.
22. Oken BS, Kishiyama S, Zajdel D, et al. Randomized controlled trial of yoga and exercise in multiple sclerosis. Neurology. 2004;62(11):2058-2064.
23. Kolasinski SL, Garfinkel M, Tsai AG, et al. Iyengar yoga for treating symptoms of osteoarthritis of the knees: a pilot study. J Altern Complement Med. 2005;11(4):689-693.
24. Ramaratnam S, Sridharan K. Yoga for epilepsy. Cochrane Database Syst Rev. 2000(3):CD001524.
25. Ray US, Mukhopadhyaya S, Purkayastha SS, et al. Effect of yogic exercises on physical and mental health of young fellowship course trainees. Indian J Physiol Pharmacol. 2001;45(1):37-53.
26. Boehde D, Porcari JP, Greany J, et al. The physiological effects of 8 weeks of yoga training. J Cardiopulm Rehabil. 2005;25(5):290.

Evidence based Yoga

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Yoga is a mind and body practice in complementary medicine with origins in ancient Indian philosophy. The various styles of yoga that people use for health purposes typically combine physical postures, breathing techniques, and meditation or relaxation. There are numerous schools of yoga. Hatha yoga, the most commonly practiced in the United States and Europe, emphasizes postures (asanas) and breathing exercises (pranayama).

Since the 1020’s researchers have been studying and publishing articles on the results of a Yoga practice. Listed below are some of the research results of Hatha Yoga and specific medical conditions. :

Utthita Trikonasana

ADHD Eighteen boys with diagnosed attention-deficit/hyperactivity disorder (ADHD) were randomly assigned to either a yoga treatment or a cooperative activities group. After 20 sessions of yoga, the boys showed improvement on a variety of indices, including oppositional behavior, emotional lability, and restlessness or impulsivity. The subjects exhibited a dose/ response curve, with those subjects who participated in additional home practice showing a greater response. The control group showed superior scores on measures of hyperactivity, anxiety, and shyness, as well as social function measures.7

Anxiety A meta-analysis of the research involving yoga interventions for anxiety and related disorders reviewed eight studies conducted during 2004. Overall, this research reported positive results, especially in cases of obsessive-compulsive disorder. However, the authors were quick to point out a generally poor quality of research techniques, inadequacies in methodology, and difficulty comparing studies.8 A Cochrane review of two RCTs that investigated the effectiveness of meditation and yoga on patients with diagnosed anxiety disorders stated that based on the available research, no distinct conclusions can be drawn on the ability of meditation and yoga to be effective for anxiety disorders.9

Asthma To determine the efficacy of Iyengar yoga practice on symptoms and perceived quality of life of people living with asthma, 62 patients with mild to moderate asthma were randomized and divided into two groups. The treatment group performed Iyengar yoga for 4 weeks, and the control group enrolled in a “stretching” program. Both groups underwent spirometry testing and recorded their bronchodilator use, symptoms, and quality of life assessments. At no point in the study did the yoga intervention group show a measured benefit in clinical indices.10

Another small RCT divided 17 subjects into a yoga treatment and a control group. The yoga group engaged in relaxation pranayama (mindful breathing) techniques, yoga postures, and meditation 3 times per week for 16 weeks. Spirometry testing showed little difference between the two groups; however, the yoga group showed improved exercise tolerance and reported relaxation as well as a more positive attitude as measured by questionnaire. This study also showed a trend toward less use of short-acting bronchodilator medication in the yoga group.11

Back pain A 12-week RCT compared viniyoga practice with conventional therapeutic back exercises or a self-help book for 101 patients with chronic low back pain. The yoga group met with one instructor for a weekly 75-minute viniyoga practice. Patients were also encouraged to practice at home daily and were given handouts and an audio CD guide. This group showed greater improvement in functional status, decreased activity restriction, and increased general health compared to the conventional exercise group or the self-help book group at 12 weeks. At 26 weeks post treatment, the conventional exercise and yoga therapy group did not show a significant difference in outcome, though at all points in time, viniyoga therapy appeared to be more effective than the self- care book. The viniyoga benefit also lasted for months after the intervention.12

Cardiovascular disease A systematic literature review of 70 studies published over the past two decades showed a trend toward beneficial changes in metabolic syndrome risk factors such as insulin resistance, lipid profiles, BP, and anthropomorphic indices. The author noted that by controlling risk factors for metabolic syndrome, a regular yoga practice might possibly reduce the risk of cardiovascular disease (CVD). It is important to note that approximately one-third of the reviewed studies were RCTs and that the majority of the others were uncontrolled or nonrandomized controlled clinical trials.4 A 2002 comprehensive review of the literature on the psychophysiological effects of hatha yoga concluded that regular hatha yoga practice and a “yoga lifestyle” have the potential to benefit CVD risk indices.5

Cardiovascular fitness A 50-minute hatha yoga routine burns 2.2 to 3.6 kcal/min, the equivalent a very slow walk. Except in persons who are very deconditioned, this type of yoga practice alone is unlikely to have a significant training effect on cardiovascular fitness, pulmonary function, body composition, or fat metabolism.13 More vigorous forms of power or vinyasa yoga require a higher energy output, depending on the method of teaching and selection of asanas (postures). One recent study demonstrated a 7% increase in VO2 max after previously sedentary subjects practiced 8 weeks of yoga training.13However, the general consensus is that yoga does not provide the significant cardiovascular stimulus necessary to enhance cardiovascular function.14

REFERENCES

1. Tindle HA, Davis RB, Phillips RS, Eisenberg DM. Trends in use of complementary and alternative medicine by US adults: 1997-2002. Altern Ther Health Med. 2005;11(1):42-49.

2. Carrico M. Yoga Journal’s Yoga Basics: The Essential Beginner’s Guide to Yoga for a Lifetime of Health and Fitness. New York, NY: Henry Holt and Company; 1997.

3. Nayak NN, Shankar K. Yoga: a therapeutic approach. Phys Med Rehabil Clin N Am. 2004;15(4): 783-798, vi.

4. Innes KE, Bourguignon C, Taylor AG. Risk indices associated with the insulin resistance syndrome, cardiovascular disease, and possible protection with yoga: a systematic review.J Am Board Fam Pract. 2005;18(6):491-519.

5. Raub JA. Psychophysiologic effects of Hatha yoga on musculoskeletal and cardiopulmonary function: a literature review. J Altern Complement Med. 2002;8(6):797-812.

6. Luskin FM, Newell KA, Griffith M, et al. A review of mind-body therapies in the treatment of musculoskeletal disorders with implications for the elderly. Altern Ther Health Med. 2000;6(2): 46-56.

7. Jensen PS, Kenny DT. The effects of yoga on the attention and behavior of boys with attentiondeficit/ hyperactivity disorder (ADHD). J Atten Disord. 2004;7(4):205-216.

8. Kirkwood G, Rampes H, Tuffrey V, et al. Yoga for anxiety: a systematic review of the research evidence. Br J Sports Med. 2005;39(12):884-891.

9. Krisanaprakornkit T, Krisanaprakornkit W, Piyavhatkul N, Laopaiboon M. Meditation therapy for anxiety disorders. Cochrane Database Syst Rev. 2006;(1):CD004998.

10. Sabina AB, Williams AL, Wall HK, et al. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005;94(5):543-548.

11. Vendanthan PK, Kesavalu LN, Murthy KC, et al. Clinical study of yoga techniques in university students with asthma: a controlled study. Allergy Asthma Proc. 1998;19(1):3-9.

12. Sherman KJ, Cherkin DC, Erro J, et al. Comparing yoga, exercise, and a self-care book for chronic low back pain: a randomized, controlled trial. Ann Intern Med. 2005;143(12):849-856.

13. Tran MD, Holly RG, Lashbrook J, Amsterdam EA. Effects of Hatha yoga practice on the healthrelated aspects of physical fitness. Prev Cardiol. 2001;4(4):165-170.

14. Clay CC, Lloyd LK, Walker JL, et al. The metabolic cost of Hatha yoga. J Strength Cond Res. 2005;19(3):604-610.

Addiction Hijacks the Brain

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You’ve probably heard of the brain’s reward network. It’s activated by basic needs — including food, water and sex — and releases a surge of the feel-good neurotransmitter dopamine when those needs are met. But it can also be hijacked by drugs, which lead to a greater dopamine release than those basic needs.

But the reward network isn’t the only brain network altered by drug use. A new review concluded that drug addiction affects six main brain networks: the reward, habit, salience, executive, memory and self-directed networks.

In 2016, a total of 20.1 million people ages 12 and older in the U.S. had a substance-use disorder, according to the National Survey on Drug Use and Health, an annual survey on drug use. And drug addiction, regardless of the substance used, had surprisingly similar effects on the addicted brain, said the review, published in the journal Neuron.

The review looked at more than 100 studies and review papers on drug addiction, all of which studied a type of brain scan called functional magnetic resonance imaging (fMRI).

More than half of the studies out there look at the effects of drug use on the reward network, said Anna Zilverstand, lead author of the new review and an assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai in New York City.

“Because we showed that the effects are very distributed across the six different networks … [we can conclude that] an approach that only looks at one of these networks isn’t really justified,” Zilverstand told Live Science. “This [finding] will hopefully lead other researchers to look beyond the reward network.”

For example, the memory network is pretty much ignored in research on substance-use disorders, Zilverstand said. This network allows humans to learn non-habit-based things, such as a new physics concept or a history lesson. Some research has suggested that in people with substance-use disorders, stress shifts the person’s learning and memory away from the memory network to the habit network, which drives automatic behavior, such as seeking and taking drugs.

Another less-studied network is the self-directed network, which is involved in self-awareness and self-reflection, the review said. In people with addictions, this network has been associated with increasing craving.

Two other networks are involved in substance-use disorders: The executive network is normally responsible for goal-maintaining and execution, but drugs can alter this network as well, reducing a person’s ability to inhibit their actions. The salience network picks up important cues in a person’s environment and redirects the individual’s attention to them. (In people with drug addiction, attention is redirected toward drugs, increasing craving and drug-seeking.)

Which comes first, the brain activity or the drug use?

“For me, the most surprising [finding] was how consistent the effects were across addictions,” Zilverstand said. What’s more, “the fact that the effects are quite independent of the specific drug use points to them being something general that might actually precede drug use rather than be a consequence of drug use.”

Zilverstand said she hopes that more studies will look at whether some people have abnormal brain activity in these six networks naturally and if that activity just gets exacerbated if they begin drug use. It’s important to know if some of these traits precede drug use; if that’s the case, it might be possible to identify people who are prone to addiction and intervene before an addiction begins, she said.

Some research has pointed toward this possibility already. For example, studies have shown that some people have “difficulties … inhibiting impulsiveness before drug use,” Zilverstand said. “Some of these impairments precede drug use, and they may become worse with more drug use, but they exist before the problem escalates.”

The good news, however, is that activity in four of these networks — executive, reward, memory and salience — moves back toward “normal” once drug use ends. “We know that four of the networks (partially — not fully) recover but not yet what happens to the other two networks,” Zilverstand said in an email.

Zilverstand added that she’s particularly excited about an ongoing study called the Adolescent Brain Cognitive Development (ABCD) Study, which is tracking 10,000 children across the U.S. from around ages 9 or 10 to age 20 (the children are now around 13). Some of these individuals will inevitably become addicted to drugs, most likely marijuana or alcohol, Zilverstand said.

“We’ll be able to see if the effects that we found [in the review] exist in youth who have not yet abused drugs,” she said, and she predicted that researchers will be able to find a lot of the effects identified in the review in the six brain networks.

The authors noted that because some regions of the brain are very small — for example, the amygdala, which is found toward the center of the brain — the studies can’t identify strong signals from those areas on brain scans. So, it’s possible that drugs affect additional networks in the brain that are hidden because of the limitations of our technologies, Zilverstand said.

“We don’t want to conclude that [those effects] don’t exist,” she said.

Positive Me

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Most people know me as a generally positive glass haft full kinda person. And it’s true, I see most everything in a positive light. This has pissed and angered more than a few over the years. Not really sure why, I suppose they expect me to react and respond to things, people, and places the way they do…. but I don’t, never have, never will.

We have the power to define the meaning of events in our lives.

I learned this as a very young child from my aunties who would visit every summer to help my mom “deal” with me. As an autistic with a heart condition who preferred tree contact more than human contact my mom struggled to know what to do with me. Of course she didn’t have to deal or do, but to just let me be …. which she eventually did (mostly).

My positivity seems to have increased over the years, (if that’s even possible). After heart surgery, multiple brain surgeries, occasional homelessness, and numerous threats of violence I remain optimistic, upbeat, and hopeful.

We do have the power to define the meaning of events in our lives. People, places, and things.

Looking out my window at the sunset

Ways to increase happiness

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The most important question to ask when you feel down

Sometimes it doesn’t feel like your brain wants you to be happy. You may feel guilty or shameful. Why?

Believe it or not, guilt and shame activate the brain’s reward center.

Despite their differences, pride, shame, and guilt all activate similar neural circuits, including the dorsomedial prefrontal cortex, amygdala, insula, and the nucleus accumbens. Interestingly, pride is the most powerful of these emotions at triggering activity in these regions — except in the nucleus accumbens, where guilt and shame win out. This explains why it can be so appealing to heap guilt and shame on ourselves — they’re activating the brain’s reward center.

And you worry a lot, too. Why? In the short term, worrying makes your brain feel a little better — at least you’re doing something about your problems.

In fact, worrying can help calm the limbic system by increasing activity in the medial prefrontal cortex and decreasing activity in the amygdala. That might seem counterintuitive, but it just goes to show that if you’re feeling anxiety, doing something about it — even worrying — is better than doing nothing.

But guilt, shame, and worry are horrible, long-term solutions. So what do neuroscientists say you should do? Ask yourself this question:

What am I grateful for?

Yeah, gratitude is awesome … but does it really affect your brain at the biological level? Yup.

You know what the antidepressant Wellbutrin does? Boosts the neurotransmitter dopamine. So does gratitude.

The benefits of gratitude start with the dopamine system, because feeling grateful activates the brain stem region that produces dopamine. Additionally, gratitude toward others increases activity in social dopamine circuits, which makes social interactions more enjoyable …

Know what Prozac does? Boosts the neurotransmitter serotonin. So does gratitude.

One powerful effect of gratitude is that it can boost serotonin. Trying to think of things you are grateful for forces you to focus on the positive aspects of your life. This simple act increases serotonin production in the anterior cingulate cortex.

I know, sometimes life lands a really mean punch in the gut and it feels like there’s nothing to be grateful for. Guess what?

Doesn’t matter. You don’t have to find anything. It’s the searching that counts.

It’s not finding gratitude that matters most; it’s remembering to look in the first place. Remembering to be grateful is a form of emotional intelligence. One study found that it actually affected neuron density in both the ventromedial and lateral prefrontal cortex. These density changes suggest that as emotional intelligence increases, the neurons in these areas become more efficient. With higher emotional intelligence, it simply takes less effort to be grateful.

And gratitude doesn’t just make your brain happy — it can also create a positive feedback loop in your relationships. So express that gratitude to the people you care about.

For more on how gratitude can make you happier and more successful.

But what happens when bad feelings completely overtake you? When you’re really in the dumps and don’t even know how to deal with it? There’s an easy answer …

Label negative feelings

You feel awful. OK, give that awfulness a name. Sad? Anxious? Angry?

Boom. It’s that simple. Sound stupid? Your noggin disagrees.

In one fMRI study, appropriately titled “Putting Feelings into Words” participants viewed pictures of people with emotional facial expressions. Predictably, each participant’s amygdala activated to the emotions in the picture. But when they were asked to name the emotion, the ventrolateral prefrontal cortex activated and reduced the emotional amygdala reactivity. In other words, consciously recognizing the emotions reduced their impact.

Suppressing emotions doesn’t work and can backfire on you.

Gross found that people who tried to suppress a negative emotional experience failed to do so. While they thought they looked fine outwardly, inwardly their limbic system was just as aroused as without suppression, and in some cases, even more aroused. Kevin Ochsner, at Columbia, repeated these findings using an fMRI. Trying not to feel something doesn’t work, and in some cases even backfires.

But labeling, on the other hand, makes a big difference.

To reduce arousal, you need to use just a few words to describe an emotion, and ideally use symbolic language, which means using indirect metaphors, metrics, and simplifications of your experience. This requires you to activate your prefrontal cortex, which reduces the arousal in the limbic system. Here’s the bottom line: describe an emotion in just a word or two, and it helps reduce the emotion.

Ancient methods were way ahead of us on this one. Meditation has employed this for centuries. Labeling is a fundamental tool of mindfulness.

Make that decision

Ever make a decision and then your brain finally feels at rest? That’s no random occurrence.

Brain science shows that making decisions reduces worry and anxiety — as well as helping you solve problems.

Making decisions includes creating intentions and setting goals — all three are part of the same neural circuitry and engage the prefrontal cortex in a positive way, reducing worry and anxiety. Making decisions also helps overcome striatum activity, which usually pulls you toward negative impulses and routines. Finally, making decisions changes your perception of the world — finding solutions to your problems and calming the limbic system.

But deciding can be hard. I agree. So what kind of decisions should you make? Neuroscience has an answer.

Make a “good enough” decision. Don’t sweat making the absolute 100% best decision. We all know being a perfectionist can be stressful. And brain studies back this up.

Trying to be perfect overwhelms your brain with emotions and makes you feel out of control.

Trying for the best, instead of good enough, brings too much emotional ventromedial prefrontal activity into the decision-making process. In contrast, recognizing that good enough is good enough activates more dorsolateral prefrontal areas, which helps you feel more in control …

So when you make a decision, your brain feels you have control. And, as I’ve talked about before, a feeling of control reduces stress. But here’s what’s really fascinating: Deciding also boosts pleasure.

Actively choosing caused changes in attention circuits and in how the participants felt about the action, and it increased rewarding dopamine activity.

We don’t just choose the things we like; we also like the things we choose.

Touch people

No, not indiscriminately; that can get you in a lot of trouble.

But we need to feel love and acceptance from others. When we don’t it’s painful. And I don’t mean “awkward” or “disappointing.” I mean actually painful.

Neuroscientists did a study where people played a ball-tossing video game. The other players tossed the ball to you and you tossed it back to them. Actually, there were no other players; that was all done by the computer program.

But the subjects were told the characters were controlled by real people. So what happened when the “other players” stopped playing nice and didn’t share the ball?

Subjects’ brains responded the same way as if they experienced physical pain. Rejection doesn’t just hurt like a broken heart; your brain feels it like a broken leg.

In fact, as demonstrated in an fMRI experiment, social exclusion activates the same circuitry as physical pain … at one point they stopped sharing, only throwing back and forth to each other, ignoring the participant. This small change was enough to elicit feelings of social exclusion, and it activated the anterior cingulate and insula, just like physical pain would.

Relationships are important to your brain’s feeling of happiness. Want to take that to the next level? Touch people.

One of the primary ways to release oxytocin is through touching. Obviously, it’s not always appropriate to touch most people, but small touches like handshakes and pats on the back are usually okay. For people you’re close with, make more of an effort to touch more often.

Touching is incredibly powerful. We just don’t give it enough credit. It makes you more persuasive, increases team performance, improves your flirting … heck, it even boosts math skills.

Touching someone you love actually reduces pain. In fact, when studies were done on married couples, the stronger the marriage, the more powerful the effect.

In addition, holding hands with someone can help comfort you and your brain through painful situations. One fMRI study scanned married women as they were warned that they were about to get a small electric shock. While anticipating the painful shocks, the brain showed a predictable pattern of response in pain and worrying circuits, with activation in the insula, anterior cingulate, and dorsolateral prefrontal cortex. During a separate scan, the women either held their husbands’ hands or the hand of the experimenter. When a subject held her husband’s hand, the threat of shock had a smaller effect. The brain showed reduced activation in both the anterior cingulate cortex and dorsolateral prefrontal cortex — that is, less activity in the pain and worrying circuits. In addition, the stronger the marriage, the lower the discomfort-related insula activity.

Sum up

Here’s what brain research says will make you happy:

  • Ask “What am I grateful for?” No answers? Doesn’t matter. Just searching helps.
  • Label those negative emotions. Give it a name and your brain isn’t so bothered by it.
  • Decide. Go for “good enough” instead of ‘best decision ever made on Earth.”
  • Hugs, hugs, hugs. Don’t text — touch.